Tetrahydrobiopterin as a novel therapeutic agent in the prevention of chronic allograft vasculopathy

Rupert Oberhuber, David Bernhard, Barbara Messner, Benno Cardini, Gregor Riede, Walter Mark, Christina Steger, Gerald Brandacher, Johann Pratschke, Katrin Watschinger, Werner Ernst & Manuel Maglione
Introduction: Chronic rejection characterized by allograft vasculopathy is still a major obstacle to long term graft survival. Among different triggers the outstanding non-immunologic factor associated with chronic allograft vasculopathy (CAV) is ischemia reperfusion injury. Recently we were able to[for full text, please go to the a.m. URL]