The reverse remodelling effect of bone-marrow-derived stem cells is independent from the site of epimyocardial cell transplantation

Mani Arsalan, Jens Garbade, Heike Aupperle, Stefan Dhein, Ardawan Rastan, Sven Lehmann, Arnaud Van Linden, Johannes Blumenstein, Thomas Walther & Friedrich-Wilhelm Mohr
Introduction: The transplantation of bone-marrow derived stem cells (BMCs) represents a promising therapy in chronic heart failure. Positive effects of transplanting these cells could be shown, but the exact mechanisms are unknown. As paracrine effects are increasingly discussed, we evaluated whether[for full text, please go to the a.m. URL]