Wnt/β-catenin protects against hypoxia-induced liver injury in mice through augmented HIF-1 signaling

Nadja Lehwald, Guo-Zhong Tao, Constanze Duhme, Wolfram Trudo Knoefel, Karl G. Sylvester & Jan Schulte Am Esch
Introduction: Hypoxia is a common cause of cellular stress that accompanies numerous liver diseases and hepatic surgery. The Wnt/β-catenin signaling pathway is a critical molecular regulator of hepatic development, regeneration and carcinogenesis. However, the role of β-catenin during[for full text, please go to the a.m. URL]