Single Nucleotide Polymorphism in A20 gene regulates TNFalpha expression in atherosclerotic plaque

Gabor Gäbel, Lesca M. Holdt, Irene Hinterseher, Daniel Teupser & Hendrik Bergert
Introduction: Up-regulation of inflammatory responses is considered a driving force of atherosclerotic lesion development. Nuclear factor (NF)-kB plays a major role in regulating these inflammatory processes. Multiple mechanisms normally ensure proper termination of NF-kB activation. In this context,[for full text, please go to the a.m. URL]