Nestin-positive cells in experimental rat renal grafts undergoing chronic allograft nephropathy

Michael Skwirba, Gabriele Fuchs-Moll, Sigrid Wilker, Hans-Dieter Müller, Winfried Padberg & Veronika Grau
Introduction: Chronic allograft nephropathy is characterized by arterial remodeling, tubular atrophy, graft fibrosis, and renal dysfunction. Its pathogenesis is poorly understood and no therapies are available. Nestin, a constituent of intermediate filaments, is a marker of progenitor cells which may[for full text, please go to the a.m. URL]