Injury rapidly induces TCR-mediated signaling responses in CD4+ T-regs but not in non-T-regs

Marc Hanschen, Goro Tajima, Fionnuala O'Leary, Kimiko Ikeda & James Lederer
Introduction: Severe injury enhances the regulatory activity of CD4+ T regulatory cells (Tregs), but the mechanisms responsible for Treg activation following injury remain unclear. Objectives of this study were (i) to test whether injury differentially activates T cell receptor (TCR) signaling [for full text, please go to the a.m. URL]