Combination therapy using antiangiogenesis and temozolomide for experimental glioma treatment

M. Czabanka, J. Bruenner, M. Topalovic, F. Heppner, A. Koch & P. Vajkoczy
Objective: Treatment of malignant glioma remains a major clinical challenge. It was the aim of our study to investigate the anti-tumor effects of combined antiangiogenic and temozolomide treatment for malignant glioma. Methods: SF126 and U87 glioma cells were implanted subcutaneously in nude mice[for full text, please go to the a.m. URL]