The neural cell adhesion molecule L1CAM confers chemoresistance to human glioblastoma progenitor cells

S. Schmelz, S. Sebens, K. Hattermann, R. Mentlein, M. Mehdorn & J. Held-Feindt
Objective: Glioblastomas are highly malignant brain tumors marked by poor prognosis and unsatisfactory response to treatments such as radio- and chemotherapy. The neural cell adhesion molecule L1CAM is expressed in various types of cancers including glioblastoma and has been demonstrated to facilitate[for full text, please go to the a.m. URL]