Investigation of retinoic acid signaling in glioma stem-like cells

M. Ratliff, B. Campos, F.S. Centner, R. Warta, C. Herold-Mende & A. Unterberg
Objective: In many cell types retinoic acid (RA) leads to differentiation and growth inhibition. Due to aberrant distribution of the RA binding proteins FABP5 and CRABP2 breast cancer cells do not differentiate but instead enter a prosurvival pathway after RA exposure. Similarly, glioblastoma stem-like[for full text, please go to the a.m. URL]