Radiosensitization of stem-like glioma cells as an effective therapeutic strategy to inhibit glioma invasion

A. Giese, J. Pruefer, C. Richter, M. Rave-Fraenk, W. Schulz-Schaeffer & E. Kim
Objective: Combined treatment including post-operative radio- and chemotherapy is the standard of care for high-grade malignant gliomas. The poor effectiveness of conventional treatment modalities is explained by defects in the core signaling pathways involved in the regulation of cell survival and [for full text, please go to the a.m. URL]