Deep brain stimulation (DBS) of the subthalamic nucleus (STN) in a rat model of Parkinson's disease upregulates neurotrophins in various brain regions

K. Faust, D. Harnack, P. Vajkoczy & A. Kupsch
Objective: High frequency stimulation (HFS) of deep brain structures has evolved as a powerful therapeutic alternative for the treatment of movement disorders. Despite its clinical success, the exact mechanisms of action have remained unknown. In addition to the immediate functional efficacy of HFS,[for full text, please go to the a.m. URL]