Expression of c-fos after deep brain stimulation of the pedunculopontine tegmental nucleus in the rat 6-hydroxydopamine Parkinson model

A. Saryyeva, K. Schwabe, M. Nakamura & J.K. Krauss
Objective: Deep brain stimulation (DBS) is increasingly used to alleviate motor dysfunction in Parkinson´s disease (PD). The pedunculopontine tegmental nucleus (PPTg) may be a potential target for DBS in PD patients with severe postural instability or freezing, whereby 25 Hz stimulation is considered[for full text, please go to the a.m. URL]