Podoplanin contributes to migration and angiogenesis in malignant glioma in vitro

S. Grau, F. Trillsch, J.C. Tonn, R. Goldbrunner, S. Fugger, E. Noessner, P. Nelson & I. Von Luettichau
Objective: Podoplanin has been shown to be widely expressed in a variety of human tumors. In brain tumors, podoplanin is expressed in a grade-dependent manner. While this protein has been shown to be involved in tumor metastasis, little is known about its biological function in gliomas. Here, we describe[for full text, please go to the a.m. URL]