Comparative epigenetic analysis of the malignant progression of pleomorphic xanthoastrocytoma

R. Martínez, V. Rohde, S. Ropero & M. Esteller
Objective: Pleomorphic xanthoastrocytoma (PXA) is a rare WHO grade II tumor accounting for less than 1% of all astrocytomas. The biological behavior of PXA is benign with a 10-year survival rate of 70%. Malignant transformation of PXA is extremely unusual. We report the exceptional case of[for full text, please go to the a.m. URL]