Systemic treatment with [211At] astatine-phenylalanine enhances survival of rats with intracranial glioblastoma

N. Borrmann, S. Friedrich, A. Walte, K. Schwabe, H.J. Hedrich, J.K. Krauss, G.J. Meyer, W.H. Knapp & M. Nakamura
Objective: Increased amino acid transport in brain tumors is used for diagnostic purposes. It has been shown that the alpha emitter astatine-211 labelled to phenylalanine (At-Phe) is taken up by glioblastoma cells in vitro. Here, we tested whether systemic intravenous treatment with At-Phe would have[for full text, please go to the a.m. URL]