Neurokinin type 1-receptor-based targeting of glioblastoma multiforme with toxin-labelled substance P

D. Cordier, M. Sailer, A. Gerber & L. Mariani
Objective: Local recurrence of glioblastoma multiforme (GBM) after standard treatment, i.e. surgery and radiochemotherapy, occurs in more than 90% of cases. Sufficient local tumor control positively correlates to improved survival. Neurokinin type 1-receptors (NK1-R) are overexpressed in GBM. In[for full text, please go to the a.m. URL]