Deep brain stimulation of the entopeduncular nucleus in rats prevents apomorphine-induced deficient sensorimotor gating

D. Posch, K. Schwabe, J.K. Krauss & G. Lütjens
Objective: Deficient sensorimotor gating induced by dopamine receptor agonists is used as an endophenotype for certain neuropsychiatric disorders such as Tourette's syndrome, schizophrenia, and attention deficit disorders. One operational measure of sensorimotor gating is prepulse inhibition (PPI)[for full text, please go to the a.m. URL]