Bioactivation of dermal scaffolds with a non-viral copolymer-protected gene vector

Ann K. Reckhenrich, Ursula Hopfner, Florian Krötz, Ziyang Zhang, Christian Koch, Mathias Kremer, Hans-Günther Machens, Christian Plank & José T. Egaña
The use of scaffolds in skin tissue engineering is accompanied with low regeneration rates and high risk of infection. In this study, we activated an FDA-approved collagen scaffold for dermal regeneration by incorporation of copolymer-protected gene vectors (COPROGs) to induce a temporary release of[for full text, please go to the a.m. URL]