LOH as predictive markers and for verification of neoplasticity/identity of cultured tumor cells

Lan Kluwe, Melanie Spyra, Theresa Häger, Markus Freytag, Victor-Felix Mautner, Max Heiland & Marco Blessmann
Loss of heterozygosity (LOH), is a frequent genetic events in tumor and can be used as predictive marker for tumor development and progression. For example, LOH of chromosomes 3p and 9p are among the most predictive markers for oral squamous cell carcinomas (OSCC). On the other hand, LOH analysis provides[for full text, please go to the a.m. URL]