Analysis of clinically theranostic relevant genes, EGFR and KRAS, in subtypes of non-small cell lung cancer (NSCLC) patients

Melanie Demes, Stefanie Scheil-Bertram, Holger Bartsch, Joachim Schirren, Servet Bölükbas, Norbert Frickhofen & Annette Fisseler-Eckhoff
Aims: Genetic alterations in KRAS and EGFR oncogenes are poorly investigated in squamous cell carcinoma (SCC). In a single study, we evaluated the frequency of these cancer relevant genes in adenocarcinoma (ADC) and SSC to gain further inside into the significance of EGFR in NSCLCs and to explore wh[for full text, please go to the a.m. URL]