Apolipoprotein E (apoE) isoforms influence bone mass and turnover in vivo

F.T. Beil, M. Dieckmann, R.P. Marshall, M. Amling, J. Herz & A. Niemeier
Questionnaire: We have previously shown that apoE -/- mice display a high bone mass phenotype due to an increased bone formation rate and that apoE inhibits murine and human osteoblasts differentiation and function through inhibition of canonical wnt signaling. Mice have only one form of apoE a[for full text, please go to the a.m. URL]