How to generate evidence for the clinical benefit of a diagnostic method

Werner Vach, Poul Flemming Hoilund-Carlsen, Oke Gerke & Wolfgang Weber
Background: Today diagnostic methods like PET/CT have to demonstrate not only their diagnostic accuracy, but also their clinical benefit [ref:1]. However, there is a lack of consensus about how to approach this aim. [ref:2]. Materials and methods: We review some basic app[for full text, please go to the a.m. URL]