Comparing copy number aberrations in pairs of tumor samples from the same patient

Jens Gietzelt, Markus Kreuz & Dirk Hasenclever
Objectives: Comparisons of paired tumor samples, i. e. primary and corresponding recurrent tumor, are performed in order to obtain insights into tumor evolution. We analyze genomic copy number aberrations measured by array comparative genomic hybridization (aCGH). A major source of bias is the difference[for full text, please go to the a.m. URL]