Radiotherapy-induced late adverse effects of tissue in breast cancer patients – results from the German MARIE(RAD) study

Petra Seibold, Irmgard Helmbold, Peter Schmezer, Rainer Claus, Johannes Claßen, Angela Hoederath, Thomas Schnabel, Odilia Popanda & Jenny Chang-Claude
Background: Radiotherapy (RT) is routinely applied after breast conserving surgery (BCS) in breast cancer patients to decrease the risk of local recurrences. However, late adverse effects of tissue such as skin alterations (e.g. telangiectasia) and fibrosis can occur as a consequence of radiotherapy[for full text, please go to the a.m. URL]