Polymorphisms in DNA repair genes modify lymphoma risk

Katja Butterbach, Odilia Popanda, Silvia De Sanjosé, Yolanda Benavente, Nikolaus Becker, Lenka Foretova, Marc Maynadie, Pierluigi Cocco, Anthony Staines, Rudolf Kaaks, Stefanie Hieke, Martin Schumacher, Paolo Boffetta, Paul Brennan & Alexandra Nieters
Introduction: The high risk of lymphoma among individuals affected by hereditary syndromes associated with aberrant repair of DNA double-strand breaks points towards an important role of this pathway in lymphomagenesis. Single nucleotide polymorphisms (SNPs) that affect DNA repair mechanisms can increase[for full text, please go to the a.m. URL]