Immunosuppressants associated with progressive multifocal leukoencephalopathy: A disproportionality analysis of spontaneous reports within the US Adverse Event Reporting System (AERS)

Niklas Schmedt, Frank Andersohn & Edeltraut Garbe
Background: Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the central nervous system. In the last years, it has gained particular attention as an adverse drug reaction (ADR) of immunosuppressive drugs, especially with the use of the monoclonal antibodies natalizumab,[for full text, please go to the a.m. URL]