Association of prion protein with cognitive functioning in humans

Lutz Philipp Breitling, Elke Raum, Christa Stegmaier, Matthias Kliegel & Hermann Brenner
Background: Recent animal studies have suggested a key role for cellular prion protein (PrPc) in the pathological consequences of amyloid plaque formation, the hallmark of Alzheimer's disease [ref:1]. This epidemiological study investigated whether serum concentrations of PrPc are associated[for full text, please go to the a.m. URL]