The role of PTHrP in meningioma bone invasion

M.A. Proescholdt, E.M. Störr, A. Lohmeier & A. Brawanski
Objective: Invasion of the adjacent bone has been shown to be a risk factor for recurrence and poor prognosis in meningiomas. However, the molecular mechanism for this process is unknown. Parathyroid hormone related protein (PTHrP) causes osteoclast activation and mediates bone metastasis in different[for full text, please go to the a.m. URL]