Spatiotemporal propagation of spreading depolarization on the human cerebral cortex after malignant hemispheric stroke

J. Woitzik, N. Hecht, A. Pinczolits, N. Sandow, S. Major, M.K.L. Winkler, S.W. Weber-Carstens, C. Dohmen, R. Graf, A.J. Strong, J.P. Dreier & P. Vajkoczy
Objective: Experimental evidence suggests that spreading depolarization (SD) is a key-phenomenon for infarct progression. Its recent detection after human brain damage in high incidence and in association with poor outcome has gained much attention. However, little is known about the spatiotemporal [for full text, please go to the a.m. URL]