The prognostic value of IDH mutations and MGMT promoter status in secondary high-grade gliomas

T. Juratli, M. Kirsch, K. Geiger, S. Souceck, G. Schackert & D. Krex
Objective: Reports about the prognostic value of IDH mutations and the promoter region of the O6-Methyl-guanyl-methyl-transferase (MGMT) gene in secondary high-grade gliomas (sHGG) are few in number. We analyzed the relationships among histology, IDH mutations, MGMT promoter status, treatment and outcome[for full text, please go to the a.m. URL]