Blocking fatty acid synthase leads to glioblastoma cell growth inhibition

S. Grube, P. Duenisch, M. Klausnitzer, R. Kalff & C. Ewald
Objective: High level of fatty acid synthase (FAS) expression have been reported in different tumors, including prostate, breast and ovarian cancer, and its inhibition reduces tumor growth in vitro and in vivo. We showed increased FAS expression level in glioblastoma WHO grade IV compared to astrocytoma[for full text, please go to the a.m. URL]