Intranasal administration: A non-invasive, direct passage for the delivery of glioma-targeting neural stem/progenitor cells

M. Reitz, M. Demestre, J. Sedlacik, H. Meissner, M. Westphal & N.O. Schmidt
Objective: Stem cell based therapies for neurological disorders including brain tumors advance continuously towards clinical trials. Optimized cell delivery to the brain remains a challenge since transplantation efficiency after direct cerebral cell injection is very low. We investigated the feasibility[for full text, please go to the a.m. URL]