mTOR as a new therapeutic target in meningiomas – expression analysis and inhibition of cell growth

J. Walter, S. Grube, A. Koch, D. Freitag, R. Kalff & C. Ewald
Objective: The protein kinase mammalian target of rapamycin (mTOR) is known to play an important role in the regulation of cell growth and has been evaluated as a target for the treatment of a variety of tumors. Increasing evidence even suggests its involvement in glioma cell survival, but to date little[for full text, please go to the a.m. URL]