Evaluation of the internal validity of guideline recommendations

H. Raatz, R. Wolff, E. Höfer, U. Siering, J. Kleijnen & A. Ruether
Background: Instruments supporting the development and assessment of guidelines, such as GRADE and AGREE, are well established. Yet sound methods in the development of a guideline are no guarantee that a recommendation is (still) valid. Usually the assessment of the internal validity of a recommendation[for full text, please go to the a.m. URL]