Survival analysis of a cohort of Clinical Practice Guidelines from the Spanish National Guideline Programme

L. Martínez García, P. Díaz Del Campo, M.D. Estrada, I. Etxeandia-Ikobaltzeta, A. Louro González, D. Rigau, F. Salcedo-Fernandez, M.D.M. Trujillo Martín & P. Alonso-Coello
Background: Little is known about how frequently Clinical Practice Guidelines (CPGs) need to be updated. Objectives: To provide empirical estimates of the average time for CPGs to become obsolete. Methods: We have randomly selected a sample of recommendations from four CPGs (Management of Major[for full text, please go to the a.m. URL]