An example of applying GRADE and an 'across studies' grading system in a guideline on asthma management in children: contrasting recommendations

M. Langendam, N. Boluyt & B. Rottier
Background Guideline developers use various systems to rate the quality of evidence underlying their recommendations. However, all have limitations. Therefore, a highly structured and transparent method was launched: GRADE. Objectives: To compare a conventional 'across studies' grading [for full text, please go to the a.m. URL]