Are clinical guideline recommendations for primary care based on research conducted in, or generalisable to, a primary care setting?

T. Stokes, N. Steel, A. Abdelhamid & H. Edwards
Background: The UK National Institute for Health and Clinical Excellence (NICE) clinical guidelines are developed from the best available evidence and apply to primary care (PC). Historically, however, much clinical research has been conducted on highly selected secondary care populations and so therelevance[for full text, please go to the a.m. URL]