Antitumor potential of SLPI promoter controlled recombinant caspase-3 expression in laryngeal carcinoma

Jia Chen, Beibei Yang, Shoude Zhang, Jingjia Ye, Zhenyu Jia & Jiang Cao
The purpose of this study is to develop a specific and efficient targeted gene therapy approach for laryngeal carcinomas. Several promoters were cloned and evaluated for transcription regulation potential. One SLPI promoter fragment (-650 to +22) showed the highest efficiency and specificity among[for full text, please go to the a.m. URL]