Exome sequencing and linkage analysis identified TNC as a novel causative gene in nonsyndromic hearing loss

Qiuju Wang, Y. Zhao, G. Tian, F. Zhao, L. Zong, D. Wang, L. Lan, Q. Li, B. Han, W. Yang, H. Yang & J. Wang
In this study, a five-generation Chinese family with progressive autosomal dominant hearing loss was mapped to a critical region spanning 28.54 Mb on chromosome 9q31.3-q34.3 by linkage analysis, which was a novel DFNA locus, assigned as DFNA56. In this interval, there were 398 reported genes. Then, [for full text, please go to the a.m. URL]