Intratympanic injection of shRNA-expressing lentivirus causes gene silencing in the inner ear in chicken

Mingliang Xiang, Yu Jia, Chenling Shen & Hao Wu
Objectives/Hypothesis: To test if intratympanic injection of shRNA-expressing lentivirus can cause gene silencing in the inner ear in chicken. Study Design: Randomized controlled trial. Methods: EFNA2 was selected as the target gene for shRNA-mediated silencing. pFU-GW-iRNA viral vector and[for full text, please go to the a.m. URL]