Modulation of Calpain 1 and 2 and local inflammation in aortic aneurysms

Isabella Kanzler, Stephanie Schack, Katharina Rolle, Andreas Zierer, Anton Moritz & Andres Beiras-Fernandez
Introduction: Calpain-1 and Calpain-2 are acute phase proteins involved in proinflammatory processes. Activation of the Calpain family has been related to vessel wall degradation in animal models, and correlated with histological alterations in the dilated aorta in Marfan patients. The aim of our study[for full text, please go to the a.m. URL]