Challenging the foregut hypothesis – Remission of Type 2 Diabetes after Roux-en Y Gastric Bypass but not after Duodeno-Jejunal Bypass in genetically diabetic rats

Florian Seyfried, Marco Bueter, Kerstin Spliethoff, Alexander Miras, Kathrin Abegg, Thomas Lutz, Christian Jurowich, Christoph-Thomas Germer & Carel Le Roux
Introduction: Bariatric surgery is currently the most effective therapeutic option to treat type 2 diabetes mellitus (T2DM) associated with morbid obesity, but the underlying mechanisms remain unclear. Roux-en-Y Gastric Bypass (RYGB) and Duodenal-Jejunal Bypass (DJB) bypass the proximal small intestine,[for full text, please go to the a.m. URL]