Microscopic transsphenoidal pituitary surgery: Collagen sponge coated with activated thrombin and fibrinogen versus Fascia lata as a treatment option for intraoperative cerebro-spinal fluid fistulas

Dominique Kuhlen, Jürgen Kreutzer, Jens Lehmberg, Michael Stoffel, Florian Ringel, Karine Sahakyan & Bernhard Meyer
Objective: Intraoperative cerebro-spinal fluid (CSF) fistula is a well-known problem during transsphenoidal pituitary surgery. Meticulous repair of the defect in the diaphragm and the sellar floor is mandatory using either periumbilical fat, a fascial graft, or a collagen sponge coated with activated[for full text, please go to the a.m. URL]