VEGF-receptor 3 as promising therapeutic target in malignant gliomas

Eugenie Gieser, Valerie Albrecht, Patrick N. Harter, Jörg-Christian Tonn, Christian Schichor & Rainer Glass
Objective: VEGF-R3 plays an important role in developmental and lymphatic angiogenesis and is expressed in high-grade gliomas, but not in the normal brain. Herein, we investigated the role of VEGF-R3 as a potential specific and direct marker for tumor associated blood-vessels and explored if VEGF-R3[for full text, please go to the a.m. URL]