Occurrence of germline AIP mutations in a series of surgically treated sporadic pituitary tumors

Isabelle Ribeiro-Pais, D. Evans, Till Burkhardt, Z. Rohani, Jens Aberle & Jörg Flitsch
Objective: In most patients the tumorgenesis of pituitary adenomas remains unclear. In sporadic, as well as hereditary adenomas, different genetic and molecular causes have been described. Recently, the inactivating gene mutations of the aryl hydrocarbon receptor protein (AIP) have become the focus [for full text, please go to the a.m. URL]