Salivary melatonin concentration and sleep patterns before and after pinealectomy in patients with pineocytoma WHO°I

Helen Slawik, Michael Stoffel, Michael Behr, Bernhard Meyer, Jens Lehmberg, Michael Wiegand & Sandro M. Krieg
Objective: The pineal gland as a melatonin-producing organ is suggested to be involved in the regulation of sleep and circadian rhythm. However, according to published data only 25–54% of patients after pinealectomy suffer from sleep disturbances (Macchi, 2004). Moreover, previous studies[for full text, please go to the a.m. URL]