Recording of negative DC potential (spreading depression) in human brain during awake neurosurgery

Maryam Khaleghi Ghadiri, Walter Stummer, Christian Ewelt, Johannes Wölfer & Ali Gorji
Objective: Spreading depression (SD) is a pathophysiological condition of the brain. The ECoG correlate of SD is a large slow negative potential change propagating at a rate of ~3 mm/min.The occurrence of SD has been demonstrated in the comatose patients suffering from cerebrovascular diseases.[for full text, please go to the a.m. URL]