Expression of human aryl hydrocarbon receptor and ARNT, its nuclear translocator, is upregulated after chemotherapy in recurrent glioblastoma multiforme

Marco Timmer, Roland Goldbrunner & Gabriele Röhn
Objective: The dioxin/aryl hydrocarbon receptor (AhR) is a transcription factor, to which a role in human cancerogenesis, cell cycle progression and transforming growth factor-β (TGF-β) has been attributed. The endogenous tumor-promoting ligand of the human AhR kynurenine was discovered[for full text, please go to the a.m. URL]