Dose-dependent effect of late outgrowth endothelial colony forming cells (ECFC) on collateral remodeling in a mouse model of chronic cerebral hypoperfusion

Nils Hecht, Stephan Marticorena-Garcia, Karen Bieback, Johannes Woitzik & Peter Vajkoczy
Objective: Bone marrow derived endothelial progenitor cells (EPC) contribute to adult blood vessel formation and may play a role in the increased collateral vessel growth seen in patients with coronary artery disease and chronic cerebral hypoperfusion. This might open the venue for future cellular therapies[for full text, please go to the a.m. URL]