Critical re-appraisal of irradiation strategies to generate bone marrow chimeras studying the microglia/macrophage compartment in the glioblastoma mouse model

Annett Müller, Susan Brandenburg, Kati Turkowski & Peter Vajkoczy
Objective: The tumor mass of glioblastoma multiforme consists of up to one third of microglia and/or macrophages. Distinguishing between both cell types is of current interest as studies in various CNS diseases suggested different effector roles. Due to the absence of specific markers, bone marrow[for full text, please go to the a.m. URL]